CV - ESCHALIER Alain

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PUBLICATIONS

Assessment of thermal sensitivity in rats using the thermal place preference test: description and application in the study of oxaliplatin-induced acute thermal hypersensitivity and inflammatory pain models

2014 - Balayssac D,Ling B,Ferrier J,Pereira B,Eschalier A,Authier N Behav Pharmacol. n°25(2) - pp 99-111

Un cœur en Auvergne pour l'Institut Analgesia, premier pôle de recherche et d'innovation sur le traitement de la douleur

2014 - Ducki S, Eschalier A, Corteval A, Bennis K, Ripoche I, Busserolles J, Courteix C L'actualité chimique n°395 - pp 29-33

Low doses of Dextromethorphan have a beneficial effect in the treatment of neuropathic pain.

2014 - Morel V,Pickering G,Etienne M,Dupuis A,Privat AM,Chalus M,Eschalier A,Daulhac L Fundam Clin Pharmacol. n°/ - pp /

T-type calcium channels in chronic pain: mouse models and specific blockers

2014 - Francois A,Laffray S,Pizzoccaro A,Eschalier A,Bourinet E Pflugers Arch n°466(4) - pp 707-17

Synthesis and structure-activity relationship study of substituted caffeate esters as antinociceptive agents modulating the TREK-1 channel.

2014 - Rodrigues N,Bennis K,Vivier D,Pereira V,Chatelain F,Chapuy E,Deokar H,Busserolles J,Lesage F,Eschalier A,Ducki S Eur J Med Chem n°75 - pp 391-402

Alleviating Pain Hypersensitivity through Activation of Type 4 Metabotropic Glutamate Receptor

2013 - Vilar B,Busserolles J,Ling B,Laffray S,Ulmann L,Malhaire F,Chapuy E,Aissouni Y,Etienne M,Bourinet E,Acher F,Pin JP,Eschalier A,Goudet C J Neurosc n°33(48) - pp 18951-65

State-dependent properties of a new T-type calcium channel blocker enhance Ca(V)3.2 selectivity and support analgesic effects

2013 - Francois A,Kerckhove N,Meleine M,Alloui A,Barrere C,Gelot A,Uebele VN,Renger JJ,Eschalier A,Ardid D,Bourinet E Pain n°154(2) - pp 283-93

Disruption of 5-HT2A Receptor-PDZ Protein Interactions Alleviates Mechanical Hypersensitivity in Carrageenan-Induced Inflammation in Rats

2013 - Wattiez AS,Pichon X,Dupuis A,Hernandez A,Privat AM,Aissouni Y,Chalus M,Pelissier T,Eschalier A,Marin P,Courteix C PLoS One n°8(9) - e74661

TAFA4, a Chemokine-like Protein, Modulates Injury-Induced Mechanical and Chemical Pain Hypersensitivity in Mice

2013 - Delfini MC,Mantilleri A,Gaillard S,Hao J,Reynders A,Malapert P,Alonso S,Francois A,Barrere C,Seal R,Landry M,Eschalier A,Alloui A,Bourinet E,Delmas P,LeFeuvre Y,Moqrich A Cell Rep n°5(2) - pp 378-88

A polyamine-deficient diet prevents oxaliplatin-induced acute cold and mechanical hypersensitivity in rats

2013 - Ferrier J,Bayet-Robert M,Pereira B,Daulhac L,Eschalier A,Pezet D,Moulinoux JP,Balayssac D PLoS One n°8(10) - e77828

Memantine, a promising drug for the prevention of neuropathic pain in rat

2013 - Morel V,Etienne M,Wattiez AS,Dupuis A,Privat AM,Chalus M,Eschalier A,Daulhac L,Pickering G Eur J Pharmacol n°721(1-3) - pp 382-90

Fatty Acid Amide Hydrolase-Dependent Generation of Antinociceptive Drug Metabolites Acting on TRPV1 in the Brain

2013 - Barriere DA,Mallet C,Blomgren A,Simonsen C,Daulhac L,Libert F,Chapuy E,Etienne M,Hogestatt ED,Zygmunt PM,Eschalier A PLoS One n°8(8) - e70690

Opiates Modulate Thermosensation by Internalizing Cold Receptor TRPM8

2013 - Shapovalov G,Gkika D,Devilliers M,Kondratskyi A,Gordienko D,Busserolles J,Bokhobza A,Eschalier A,Skryma R,Prevarskaya N Cell Rep n°4(3) - pp 504-15

Peripheral contribution of NGF and ASIC1a to colonic hypersensitivity in a rat model of irritable bowel syndrome

2013 - Matricon J,Muller E,Accarie A,Meleine M,Etienne M,Voilley N,Busserolles J,Eschalier A,Lazdunski M,Bourdu S,Gelot A,Ardid D Neurogastroenterol Motil n°25(11) - e740-54

Animal Models of Toxic and Metabolic Neuropathic pain

2013 - Courteix C,Ferrier J,Marchand F,Authier N,Dupuis A,Balayssac D,Eschalier A Pain Models: Translation Relevance and Applications

Monoacylglycerols Activate TRPV1 – A Link between Phospholipase C and TRPV1

2013 - Zygmunt PM,Ermund A,Movahed P,Andersson DA,Simonsen C,Jonsson BA,Blomgren A,Birnir B,Bevan S,Eschalier A,Mallet C,Gomis A,Hogestatt ED PLoS One n°8(12) - e81618

Activation of TREK-1 by morphine results in analgesia without adverse side effects

2013 - Devilliers M,Busserolles J,Lolignier S,Deval E,Pereira V,Alloui A,Christin M,Mazet B,Delmas P,Noel J,Lazdunski M,Eschalier A Nat Commun n°4 - pp 2941

Study of emotional and cognitive impairments in mononeuropathic rats: effect of duloxetine and gabapentin

2012 - Gregoire S,Michaud V,Chapuy E,Eschalier A,Ardid D Pain n°153(8) - pp 1657-63

Paracetamol: a promising ancestor

2012 - Mallet C,Barriere DA,Eschalier A Therapie n°67(4) - pp 227-81

Stereoselective synthesis and in vivo evaluation of the analgesic activity of polysubstituted bispidines

2012 - Plas A,Marchand F,Eschalier A,Troin Y,Chalard P European J Org Chem - In Press

Study of emotional and cognitive impairments in mononeuropathic rats: effect of duloxetine and gabapentin

2012 - Gregoire S,Michaud V,Chapuy E,Eschalier A,Ardid D Pain n°153(8) - pp 1657-63

Functional dysbiosis within the gut microbiota of patients with constipated-irritable bowel syndrome

2012 - Chassard C,Dapoigny M,Scott KP,Crouzet L,Del-Homme C,Marquet P,Martin JC,Pickering G,Ardid D,Eschalier A,Dubray C,Flint HJ,Bernalier-Donadille A Aliment Pharmacol Ther n°35(7) - pp 828-38

A prospective study of neuropathic pain induced by thoracotomy: incidence, clinical description, and diagnosis

2011 - Guastella V,Mick G,Soriano C,Vallet L,Escande G,Dubray C,Eschalier A Pain n°152(1) - pp 74-81

T-type calcium channels contribute to colonic hypersensitivity in a rat model of irritable bowel syndrome

2011 - Marger F,Gelot A,Alloui A,Matricon J,Ferrer JF,Barrere C,Pizzoccaro A,Muller E,Nargeot J,Snutch TP,Eschalier A,Bourinet E,Ardid D Proc Natl Acad Sci U S A n°108(27) - pp 11268-73

Tropisetron and paracetamol association in post-operative patients

2011 - Pickering G,Faure M,Commun F,De-Boissy EC,Roche G,Mom T,Simen E,Dubray C,Eschalier A,Gilain L Fundam Clin Pharmacol n°26(3) - pp 432-7

Acid-sensing ion channels in postoperative pain

2011 - Deval E,Noel J,Gasull X,Delaunay A,Alloui A,Friend V,Eschalier A,Lazdunski M,Lingueglia E J Neurosci n°31(16) - pp 6059-66

Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors

2011 - Descoeur J,Pereira V,Pizzoccaro A,Francois A,Ling B,Maffre V,Couette B,Busserolles J,Courteix C,Noel J,Lazdunski M,Eschalier A,Authier N,Bourinet E EMBO Mol Med n°3(5) - pp 266-78

Oral magnesium treatment in patients with neuropathic pain: a randomized clinical trial

2011 - Pickering G,Morel V,Simen E,Cardot JM,Moustafa F,Delage N,Picard P,Eschalier S,Boulliau S,Dubray C Magnes res n°24(2) - pp 28-35

Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?

2011 - Wattiez AS,Libert F,Privat AM,Loiodice S,Fialip J,Eschalier A,Courteix C Br J Pharmacol n°163(4) - pp 792-803

T-type calcium channels contribute to colonic hypersensitivity in a rat model of irritable bowel syndrome

2011 - Marger F,Gelot A,Alloui A,Matricon J,Ferrer JF,Barrere C,Pizzoccaro A,Muller E,Nargeot J,Snutch TP,Eschalier A,Bourinet E,Ardid D Proc Natl Acad Sci U S A n°108(27) - pp 11268-73

Nav1.9 channel contributes to mechanical and heat pain hypersensitivity induced by subacute and chronic inflammation

2011 - Lolignier S,Amsalem M,Maingret F,Padilla F,Gabriac M,Chapuy E,Eschalier A,Delmas P,Busserolles J PLoS One n°6(8) - e23083

A prospective study of neuropathic pain induced by thoracotomy: incidence, clinical description, and diagnosis

2011 - Guastella V,Mick G,Soriano C,Vallet L,Escande G,Dubray C,Eschalier A Pain n°152(1) - pp 74-81

Phosphorylation of spinal N-methyl-d-aspartate receptor NR1 subunits by extracellular signal-regulated kinase in dorsal horn neurons and microglia contributes to diabetes-induced painful neuropathy

2011 - Daulhac L,Maffre V,Mallet C,Etienne M,Privat AM,Kowalski-Chauvel A,Seva C,Fialip J,Eschalier A Eur J Pain n°15(2) - 169.e1-12

Chemotherapy-induced peripheral neuropathies: from clinical relevance to preclinical evidence

2011 - Balayssac D,Ferrier J,Descoeur J,Ling B,Pezet D,Eschalier A,Authier N Expert Opin Drug Saf n°10(3) - pp 407-17

TRPV1 in brain is involved in acetaminophen-induced antinociception

2010 - Mallet C,Barriere D,Ermund A,Jonsson BA,Eschalier A,Zygmunt PM,Hogestatt ED PLoS One n°5(9) - e12748

Disrupting 5-HT(2A) receptor/PDZ protein interactions reduces hyperalgesia and enhances SSRI efficacy in neuropathic pain

2010 - Pichon X,Wattiez AS,Becamel C,Ehrlich I,Bockaert J,Eschalier A,Marin P,Courteix C Mol Ther n°18(8) - pp 1462-70

Magnesium attenuates chronic hypersensitivity and spinal cord NMDA receptor phosphorylation in a rat model of diabetic neuropathic pain

2010 - Rondon L,Privat AM,Daulhac L,Davin N,Mazur A,Fialip J,Eschalier A,Courteix C J Physiol n°588(Pt 21) - pp 4205-15

The transient receptor potential channel TRPM8 is inhibited via the alpha 2A adrenoreceptor signaling pathway

2010 - Bavencoffe A,Gkika D,Kondratskyi A,Beck B,Borowiec AS,Bidaux G,Busserolles J,Eschalier A,Shuba Y,Skryma R,Prevarskaya N J Biol Chem n°285(13) - pp 9410-9

The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception

2009 - Noel J,Zimmermann K,Busserolles J,Deval E,Alloui A,Diochot S,Guy N,Borsotto M,Reeh P,Eschalier A,Lazdunski M EMBO J n°28(9) - pp 1308-18

Increase in morphine antinociceptive activity by a P-glycoprotein inhibitor in cisplatin-induced neuropathy

2009 - Balayssac D,Cayre A,Ling B,Maublant J,Penault-Llorca F,Eschalier A,Coudore F,Authier N Neurosci Lett n°465(1) - pp 108-12

T-type calcium channel inhibition underlies the analgesic effects of the endogenous lipoamino acids

2009 - Barbara G,Alloui A,Nargeot J,Lory P,Eschalier A,Bourinet E,Chemin J J Neurosci n°29(42) - pp 13106-14

Animal models of chemotherapy-evoked painful peripheral neuropathies

2009 - Authier N,Balayssac D,Marchand F,Ling B,Zangarelli A,Descoeur J,Coudore F,Bourinet E,Eschalier A Neurotherapeutics n°6(4) - pp 620-9

The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception

2009 - Noel J,Zimmermann K,Busserolles J,Deval E,Alloui A,Diochot S,Guy N,Borsotto M,Reeh P,Eschalier A,Lazdunski M Embo J n°28(9) - pp 1308-18

Acetaminophen reinforces descending inhibitory pain pathways

2008 - Pickering G,Esteve V,Loriot MA,Eschalier A,Dubray C Clin Pharmacol Ther n°84(1) - pp 47-51

 
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